Oxolinic Acid EP Impurity A
OXOLINIC ACID IMPURITY A
CAS: 26893-27-6
Molecular Formula: C11H7NO5
Oxolinic Acid EP Impurity A - Names and Identifiers
Oxolinic Acid EP Impurity A - Physico-chemical Properties
| Molecular Formula | C11H7NO5 |
| Molar Mass | 233.18 |
| Density | 1.678±0.06 g/cm3(Predicted) |
| Melting Point | >290 °C(Solv: N,N-dimethylformamide (68-12-2)) |
| Boling Point | 459.2±45.0 °C(Predicted) |
| Appearance | neat |
| pKa | 0.85±0.20(Predicted) |
Oxolinic Acid EP Impurity A - References
| quinolinone bactericide | , it is white with yellow-white columnar crystal or crystalline powder at room temperature, odorless and tasteless, has strong antibacterial effect on Gram-negative bacteria and some positive bacteria, and has no cross resistance to antibiotics, but it has no antibacterial effect on fungi and Mycobacterium tuberculosis, and has the advantages of low dosage and good antibacterial effect. It is mainly used for the treatment of bacterial diseases of fish and shrimp, it is considered to be one of the ideal drugs for the treatment of aquatic animal diseases, and has a strong antibacterial activity against Vibrio anguillarum, Aeromonas hydrophila and other fish pathogens. So the eel and other aquatic animals are widely used in Japan and Taiwan province, and the PH has a slight effect on it in the marine culture, and the dosage of the drug should be increased in alkaline environment. Oxolinic acid has little toxicity, acute, toxicity test of carp oral median lethal dose (I. E. Under the influence of a certain concentration of the drug can make 50% of the time of individual death) for 4000mg/kg or more. And the use of the drug must be stopped before 25 days, otherwise excessive residues, the Japanese market banned imports, Taiwan increased Oxolinic acid (Oxolinic acid) in fish, shrimp, eggs, cattle, pigs, chicken muscle, fat, liver and kidney of the thirteen items of residue tolerance.
Last Update：2024-04-09 21:04:16
